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Oligonucleotide Analogues with Integrated Bases and Backbone. Part 21
Author(s) -
Bogliotti Nicolas,
Vasella Andrea
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900075
Subject(s) - chemistry , oligonucleotide , nucleobase , stereochemistry , combinatorial chemistry , crystallography , dna , biochemistry
Gelation of organic solvents by the A*[s]U ( * ) dinucleosides 1 and 2 requires the formation of linear associates cross‐linked by H‐bonding involving either the nucleobase or HOCH 2 C(6/I). This is evidenced by the absence of gel formation of the N 6 ‐methyladenosine analogue 5 of 1 and the dehydroxy analogue 4 of 2 .
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