Premium
Stereoselective Total Synthesis of Xestodecalactone C
Author(s) -
Rajesh Karuturi,
Suresh Vangaru,
Selvam Jondoss Jon Paul,
Bhujanga Rao Chitturi,
Venkateswarlu Yenamandra
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900068
Subject(s) - chemistry , stereoselectivity , total synthesis , intramolecular force , friedel–crafts reaction , electrophile , natural product , acylation , polyketide , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , biosynthesis , enzyme
A simple and highly efficient stereoselective total synthesis of xestodecalactone C ( IIb ), a polyketide natural product, was achieved ( Scheme 2 ). The synthesis involved Keck 's asymmetric allylation, a iodine‐induced electrophilic cyclization, and an intramolecular Friedel – Crafts acylation as key steps.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom