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New Diterpenoid Alkaloids from Aconitum recemulosum Franch .
Author(s) -
Ge YongHui,
Mu ShuZhen,
Yang ShiYing,
Lu Yang,
Zhang JianXin,
Wang Ye,
Hao XiaoJiang
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900065
Subject(s) - chemistry , aconitum , terpenoid , stereochemistry , ranunculaceae , alkaloid , botany , biology
Two new diterpenoid alkaloids, racemulosines A ( 1 ) and B ( 2 ), were isolated from the roots of Aconitum racemulosum Franch . The structures of the new alkaloids were elucidated by analysis of physical and spectroscopic data, and the structure of 1 was further confirmed by a single‐crystal X‐ray diffraction analysis. Furthermore, compound 1 , at 2.25⋅10 −4 mol/l, showed moderate activity against platelet aggregation induced by PAF (platelet‐activation factor).