Premium
Lignans from the Bark of Zanthoxylum planispinum
Author(s) -
Yang GuangZhong,
Hu Yun,
Yang Bo,
Chen Yu
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900055
Subject(s) - chemistry , lignan , zanthoxylum , rutaceae , bark (sound) , antibacterial activity , octane , stereochemistry , traditional medicine , organic chemistry , bacteria , botany , physics , genetics , acoustics , biology , medicine
A new dimeric lignan, named biplanispine A ( 1 ) which represents the first example of a dimeric 2,6‐diaryl‐3,7‐dioxabicyclo[3.3.0]octane skeleton from a Rutaceae plant, together with 13 known lignans 2 – 14 , was isolated from the bark of Zanthoxylum planispinum. Their structures were elucidated by spectroscopic methods, especially 2D‐NMR techniques. All isolated compounds were evaluated for their antibacterial activities by the disc diffusion method. Compounds 7 and 9 showed interesting antibacterial activities at 200 μg/disc; they were as effective as kanamycin sulfate at 10 μg/disc against Staphylococcus aureus and Bacillus subtilis.