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Cycloheximide Derivatives from the Fruits of Dipteronia dyeriana
Author(s) -
Shi YaNa,
Zhou YiPing,
Long ChunLin,
Li MaLin,
Wang YueHu,
Li XingYu,
Guo Rong,
Wang HongSheng
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200900007
Subject(s) - chemistry , cycloheximide , phytochemical , antifungal , stereochemistry , isolation (microbiology) , biochemistry , microbiology and biotechnology , protein biosynthesis , biology
The phytochemical investigation of Dipteronia dyeriana (Aceraceae) resulted in the isolation and identification of three new cycloheximide derivatives: dipteronines A–C ( 1 – 3 ). Their structures were elucidated based on the 1D‐ and 2D‐NMR spectra. Dipteronine A ( 1 ) is the first example of a 10,11‐secocycloheximide. Cytotoxic and antifungal activities of these isolates were also evaluated.