Novel and Highly Effective Method for the Trimethylsilylation of Alcohols and Phenols with Hexamethyldisilazane (HMDS), Catalyzed by I 2  Generated  in situ  Using Fe(NO 3 ) 3 ⋅9 H 2 O/NaI under Heterogeneous and Neutral Conditions | Zendy

Khazaei Ardeshir | Zendy; Rahmati Sadegh | Zendy; Rostami Amin | Zendy

Premium

Novel and Highly Effective Method for the Trimethylsilylation of Alcohols and Phenols with Hexamethyldisilazane (HMDS), Catalyzed by I 2 Generated in situ Using Fe(NO 3 ) 3 ⋅9 H 2 O/NaI under Heterogeneous and Neutral Conditions

Author(s) -

Khazaei Ardeshir,

Rahmati Sadegh,

Rostami Amin

Publication year - 2009

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200900002

Subject(s) - chemistry , phenols , yield (engineering) , in situ , catalysis , organic chemistry , metallurgy , materials science

Structurally diverse alcohols and phenols were trimethylsilylated in a clean and efficient reaction with hexamethyldisilazane (HMDS) based on the use of I 2 generated in situ from Fe(NO 3 ) 3 ⋅9 H 2 O/NaI. The reaction occurs very rapid in good‐to‐high yield in CH 2 Cl 2 at room temperature, and the use of toxic and corrosive molecular I 2 is avoided.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research