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Lignans from the Bark of Magnolia kobus
Author(s) -
Lee HakJu,
Seo SeonMi,
Lee OhKyu,
Jo HyunJin,
Kang HaYoung,
Choi DonHa,
Paik KiHyon,
Khan Merajuddin
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890256
Subject(s) - chemistry , dept , bark (sound) , two dimensional nuclear magnetic resonance spectroscopy , magnoliaceae , stereochemistry , lignan , botany , physics , acoustics , biology
Abstract The Et 2 O‐soluble fraction from the bark of Magnolia kobus led to the isolation of two new lignans, (+)‐(7 α ,7′ α ,8 α ,8′ α )‐3′,4,4′,5,5′‐pentamethoxy‐7,9′: 7′,9‐diepoxylignan‐3‐ol ( 1 ) and (+)‐(7 α ,7′ α ,8 α ,8′ α )‐4,5‐dimethoxy‐3′,4′‐(methylenedioxy)‐7,9′: 7′,9‐diepoxylignan‐3‐ol ( 2 ), along with five known lignans 3 – 7 . Their structures were established on the basis of various spectroscopic analyses including 1D‐ ( 1 H, 13 C, and DEPT) and 2D‐NMR (COSY, NOESY, HMQC, and HMBC) and by comparison of their spectral data with those of related compounds.