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Limonoids from the Twigs and Leaves of Chukrasia tabularis
Author(s) -
Zhang ChuanRui,
Yang ShengPing,
Chen XueQin,
Wu Yan,
Zhen XueChu,
Yue JianMin
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890254
Subject(s) - chemistry , potassium , stereochemistry , potassium channel , botany , organic chemistry , biophysics , biology
Seven new limonoids, tabularisins J–P ( 1 – 7 , resp.), together with eight known compounds, were isolated from the twigs and leaves of Chukrasia tabularis. Their structures were determined primarily by spectroscopic methods. The potassium channel blocking activities of some of these isolates were evaluated, and a few of them exerted significant activities on the delayed rectifier ( I K ) K + current.