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Triterpenoids from Eucalyptus camaldulensis Dehnh . Tissue Cultures
Author(s) -
Tsiri Dimitroula,
Aligiannis Nektarios,
Graikou Konstantia,
Spyropoulos Caroline,
Chinou Ioanna
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890226
Subject(s) - betulinic acid , eucalyptus camaldulensis , chemistry , ursolic acid , oleanolic acid , terpene , triterpenoid , terpenoid , traditional medicine , stereochemistry , organic chemistry , chromatography , botany , eucalyptus , biology , medicine , genetics , alternative medicine , pathology
A chemical study on tissue cultures from leaves and flowers of E. camaldulensis Dehnh . afforded the new natural product (2 α ,3 β )‐2,3,23‐trihydroxy‐13,28‐epoxyurs‐11‐en‐28‐one (dryobalanolide) together with the known pentacyclic triterpenoids: betulinic acid, oleanolic acid, ursolic acid, (2 α ,3 β )‐2,3,23‐trihydroxyolean‐12‐en‐28‐oic acid (arjunolic acid), (2 α ,3 β )‐2,3,23‐trihydroxyurs‐12‐en‐28‐oic acid (asiatic acid), (2 α )‐2‐hydroxyursolic acid, (2 α )‐2‐hydroxyoleanolic acid (maslinic acid), as well as β ‐sitosterol. The extracts and the isolated compounds were evaluated against eleven human pathogenic microorganisms, exhibiting a very interesting antibacterial spectrum of activities.