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New Antioxidant Phenolic Glucosides from Viburnum dilatatum
Author(s) -
Wu Bin,
Wu Saiwei,
Qu Haibin,
Cheng Yiyu
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890199
Subject(s) - chemistry , dpph , antioxidant , superoxide , radical , glycoside , stereochemistry , organic chemistry , botany , enzyme , biology
Chemical investigation of the fruits of Viburnum dilatatum Thunb. resulted in the isolation and characterization of four new phenolic glycosides, jiamiziosides A–D ( 1 – 4 ), together with five known compounds. Their structures were established by spectroscopic means and by comparison with the literature values. The antioxidant activities of the new isolates were determined against 2,2‐diphenyl‐1‐picrylhydrazyl (=2,2‐diphenyl‐1‐(2,4,6‐trinitrophenyl)hydrazinyl; DPPH) and superoxide radicals. Among the compounds tested, jiamizioside C ( 3 ) possesses the most potent inhibitory scavenging effect on DPPH and superoxide radicals with IC 50 values of 16.8 and 17.8 μ M , respectively.