New Antioxidant Phenolic Glucosides from  Viburnum dilatatum | Zendy

Wu Bin | Zendy; Wu Saiwei | Zendy; Qu Haibin | Zendy; Cheng Yiyu | Zendy

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New Antioxidant Phenolic Glucosides from Viburnum dilatatum

Author(s) -

Wu Bin,

Wu Saiwei,

Qu Haibin,

Cheng Yiyu

Publication year - 2008

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200890199

Subject(s) - chemistry , dpph , antioxidant , superoxide , radical , glycoside , stereochemistry , organic chemistry , botany , enzyme , biology

Chemical investigation of the fruits of Viburnum dilatatum Thunb. resulted in the isolation and characterization of four new phenolic glycosides, jiamiziosides A–D ( 1 – 4 ), together with five known compounds. Their structures were established by spectroscopic means and by comparison with the literature values. The antioxidant activities of the new isolates were determined against 2,2‐diphenyl‐1‐picrylhydrazyl (=2,2‐diphenyl‐1‐(2,4,6‐trinitrophenyl)hydrazinyl; DPPH) and superoxide radicals. Among the compounds tested, jiamizioside C ( 3 ) possesses the most potent inhibitory scavenging effect on DPPH and superoxide radicals with IC 50 values of 16.8 and 17.8 μ M , respectively.

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