Synthesis of Derivatives of the Optically Active  β ‐Amino Acids from (+)‐Car‐2‐ene | Zendy

Koneva Ekaterina A. | Zendy; Volcho Konstantin P. | Zendy; Gatilov Yuri V. | Zendy; Korchagina Dina V. | Zendy; Salnikov Georgi E. | Zendy; Salakhutdinov Nariman F. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Synthesis of Derivatives of the Optically Active β ‐Amino Acids from (+)‐Car‐2‐ene

Author(s) -

Koneva Ekaterina A.,

Volcho Konstantin P.,

Gatilov Yuri V.,

Korchagina Dina V.,

Salnikov Georgi E.,

Salakhutdinov Nariman F.

Publication year - 2008

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200890197

Subject(s) - chemistry , optically active , isocyanate , sulfuryl chloride , chloride , ene reaction , ion , organic chemistry , medicinal chemistry , polyurethane

The reaction of (+)‐car‐2‐ene ( 4 ) with chlorosulfonyl isocyanate (=sulfuryl chloride isocyanate; ClSO 2 NCO) led to the tricyclic lactams 6 and 8 corresponding to the initial formation both of the tertiary carbenium and α ‐cyclopropylcarbenium ions ( Scheme 2 ). A number of optically active derivatives of β ‐amino acids which are promising compounds for further use in asymmetric synthesis were synthesized from the lactams (see 16, 17 , and 19 – 21 in Scheme 3 ).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research