Premium
A New Triterpene and New Sesquiterpenes from the Roots of Ligularia sagitta
Author(s) -
Li PingLin,
Jia ZhongJian
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890188
Subject(s) - triterpene , chemistry , oleanane , sesquiterpene , stereochemistry , terpene , sagitta , biology , medicine , alternative medicine , pathology , fishery , fish <actinopterygii> , otolith
One new triterpene and seven new eremophilane‐type sesquiterpenes were isolated from the roots of Ligularia sagitta , among them 1a , an O ‐acetylated oleanane type triterpene, 2a and 3a , two 11‐nor eremophilane‐type sesquiterpenes, 4a, 5 , and 6 , three standard eremophilane‐type sesquiterpenes, and 7 and 8 , two tri‐nor eremophilane‐type sesquiterpenes. Their structures were established by extensive spectral analyses (1D, 2D‐NMR, IR, and MS). Compound 1a showed moderate cytotoxicity against two tumor cell lines.