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Three Escin‐Like Triterpene Saponins: Assamicins VI, VII, and VIII from the Seeds of Aesculus assamica Griff
Author(s) -
Liu HongWei,
Wang ManYuan,
Song XueYing,
Xia Ying,
Zhao YiSong,
Song XiaoHong,
Jiang MiaoMiao,
Zhang Xue,
Gao Hao,
Wang NaiLi,
Yao XinSheng
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890186
Subject(s) - chemistry , triterpene , saponin , stereochemistry , triterpenoid , terpene , medicine , alternative medicine , pathology
Three new escin‐like triterpene saponins, assamicins VI ( 1 ), VII ( 2 ), and VIII ( 3 ), were isolated from the seeds of A. assamica , together with a known saponin, isoescin Ib ( 4 ). Their structures were established as 28‐ O ‐acetyl‐21‐ O ‐(3,4‐di‐ O ‐angeloyl‐6‐deoxy‐ β ‐glucopyranosyl)‐3‐ O ‐{ O ‐ β ‐glucopyranosyl‐(1→2)‐O‐[ β ‐glucopyranosyl‐(1→4)]‐ β ‐glucopyranuronosyl}protoaescigenin ( 1 ), 21‐ O ‐angeloyl‐3‐ O ‐{ O ‐ α ‐rhamnopyranosyl‐(1→2)‐ O ‐[ β ‐glucopyranosyl‐(1→3)]‐ β ‐glucopyranuronosyl}protoaescigenin ( 2 ), and 21‐ O ‐angeloyl‐3‐ O ‐{ O ‐[ β ‐glucopyranosyl‐(1→3)]‐ β ‐glucopyranuronosyl}protoaescigenin ( 3 ) on the basis of spectroscopic analysis (protoaescigenin=(3 β ,4 β ,16 α ,21 β ,22 α )‐olean‐12‐ene‐3,16,21,22,23,28‐hexol; angelic acid=(2 Z )‐2‐methylbut‐2‐enoic acid).