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Tricycloalternarenes A – E: Five New Mixed Terpenoids from the Endophytic Fungal Strain Alternaria alternata Ly83
Author(s) -
Yuan Lin,
Zhao PeiJi,
Ma Juan,
Li GuoHong,
Shen YueMao
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890172
Subject(s) - alternaria alternata , chemistry , terpenoid , strain (injury) , fungus , plant use of endophytic fungi in defense , stereochemistry , terpene , botany , biology , anatomy
Five new mixed terpenoids, tricycloalternarenes (TCAs) A–E ( 1 – 5 ), together with two known compounds, TCA 1b ( 6 ) and TCA 2b ( 7 ), were isolated from the solid‐state‐cultured endophytic fungus Alternaria alternata of Maytenus hookeri. Their structures were identified by extensive spectroscopic (especially 2D‐NMR) experiments. Compound 7 showed weak activity against human tumor cell lines by MTT assay.