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New Indole Alkaloids from Kopsia. Alkaloid Variation in Kopsia singapurensis
Author(s) -
Subramaniam G.,
Kam TohSeok
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890098
Subject(s) - chemistry , alkaloid , indole test , indole alkaloid , apocynaceae , stereochemistry , bark (sound) , organic chemistry , botany , forestry , geography , biology
Five new indole alkaloids, viz. , kopsiloscine G ( 2 ), kopsidarine ( 4 ), kopsimaline F ( 6 ), kopsidine C N ‐oxide ( 7 ), and aspidophylline B ( 9 ), in addition to 17 other known alkaloids, were obtained from the leaf and stem‐bark extract of the Malaysian Kopsia singapurensis. The structures were determined by using NMR and MS analysis. The results are compared with the alkaloidal composition of another sample of K. singapurensis , collected from the same location but at a different time of the year, as well as with other samples of K. singapurensis collected from different locations.