One‐Pot Four‐Component Synthesis of Tetrasubstituted Pyrroles | Zendy

Kassaee M. Z. | Zendy; Masrouri Hassan | Zendy; Movahedi Farnaz | Zendy; Partovi Tayyebeh | Zendy

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One‐Pot Four‐Component Synthesis of Tetrasubstituted Pyrroles

Author(s) -

Kassaee M. Z.,

Masrouri Hassan,

Movahedi Farnaz,

Partovi Tayyebeh

Publication year - 2008

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200890027

Subject(s) - chemistry , acetylenedicarboxylate , triphenylphosphine , ammonium acetate , component (thermodynamics) , one pot synthesis , dimethyl acetylenedicarboxylate , organic chemistry , ammonium , butane , in situ , medicinal chemistry , catalysis , cycloaddition , physics , high performance liquid chromatography , thermodynamics

A convenient one‐pot four‐component synthesis of tetrasubstituted pyrroles was carried out through the reaction of butane‐2,3‐dione with α ‐aminophosphorous ylides, obtained in situ from the 1 : 1 : 1 addition reaction between triphenylphosphine, dialkyl acetylenedicarboxylate, and ammonium acetate.

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