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One‐Pot Four‐Component Synthesis of Tetrasubstituted Pyrroles
Author(s) -
Kassaee M. Z.,
Masrouri Hassan,
Movahedi Farnaz,
Partovi Tayyebeh
Publication year - 2008
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200890027
Subject(s) - chemistry , acetylenedicarboxylate , triphenylphosphine , ammonium acetate , component (thermodynamics) , one pot synthesis , dimethyl acetylenedicarboxylate , organic chemistry , ammonium , butane , in situ , medicinal chemistry , catalysis , cycloaddition , physics , high performance liquid chromatography , thermodynamics
A convenient one‐pot four‐component synthesis of tetrasubstituted pyrroles was carried out through the reaction of butane‐2,3‐dione with α ‐aminophosphorous ylides, obtained in situ from the 1 : 1 : 1 addition reaction between triphenylphosphine, dialkyl acetylenedicarboxylate, and ammonium acetate.