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Tuberculariols A – C, New Sesquiterpenes from the Mutant Strain M‐741 of Tubercularia sp. TF5
Author(s) -
Xu Ren,
Wang MingZi,
Lu ChunHua,
Zheng ZhongHui,
Shen YueMao
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200800451
Subject(s) - chemistry , strain (injury) , stereochemistry , mutant , two dimensional nuclear magnetic resonance spectroscopy , biochemistry , gene , medicine
Three new sesquiterpenes, tuberculariols A–C ( 1 – 3 , resp.), were isolated from the mutant strain M‐741 of Tubercularia sp. TF5, an endophytic fungus of Taxus mairei. Their structures were elucidated by spectroscopic analyses including 1D‐ and 2D‐NMR experiments, and HR‐Q‐TOF‐MS. Antitumor and antibacterial properties of these compounds were evaluated.