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Triterpenoids and Saponins from the Leaves of Uncaria hirsuta
Author(s) -
Xin WenBo,
Chou GuiXin,
Wang ZhengTao
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200800312
Subject(s) - chemistry , triterpenoid , terpene , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , lactone , chromatography , ethyl ester , organic chemistry
Three new triterpenoids, (3 β )‐3‐hydroxy‐27‐noroleano‐13(28)‐lactone ( 1 ), (22 α )‐22‐hydroxy‐3‐oxo‐urs‐12‐ene‐27,28‐dioic acid ( 4 ), and (3 β )‐3‐( β ‐ D ‐glucopyranosyloxy)‐12‐oxopyroquinovic acid β ‐ D ‐glucopyranosyl ester ( 7 ), together with four known compounds, pyrocincholic acid ethyl ester ( 2 ), pyrocincholic acid ( 3 ), quinovic acid ( 5 ), and (3 β )‐3‐( β ‐ D ‐quinovopyranosyloxy)pyrocincholic acid β ‐ D ‐glucopyranosyl ester ( 6 ), were isolated from the EtOH extract of the leaves of Uncaria hirsuta Haviland . Their structures were determined by means of spectroscopic analyses, including HR‐ESI‐MS and 2D‐NMR techniques. The configuration of 1 was confirmed by X‐ray analysis; 2 is an artefact, as verified by the HPLC and LC/MS analysis.