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A New Sesquiterpene from Ximenia americana Linn.
Author(s) -
de Araújo Mônica R. S.,
Monte Francisco J. Q.,
BrazFilho Raimundo
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200800289
Subject(s) - chemistry , sesquiterpene , human breast , steroid , cancer cell lines , two dimensional nuclear magnetic resonance spectroscopy , traditional medicine , stereochemistry , cell culture , cancer , biochemistry , cancer cell , hormone , biology , genetics , medicine
AbstractThe new sesquiterpene 1 , named ximonicane, and the known stigmastane steroid 2 were isolated from the EtOH extract of the stems of Ximenia americana. Spectroscopic methods, including 2D‐NMR techniques, have been used to characterize 1 and assign all the signals of the 1 H‐ and 13 C‐NMR spectra of 1 . Ximonicane did not inhibit the growth of HL‐60 (human leukemia), HTC‐8 (human colon), and MDA‐MB‐435 (human breast cancer) cell lines.