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Protolimonoids and Limonoids from the Chinese Mangrove Plant Xylocarpus granatum
Author(s) -
Cui Jianxin,
Deng Zhiwei,
Xu Minjuan,
Proksch Peter,
Li Qingshan,
Lin Wenhan
Publication year - 2009
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200800177
Subject(s) - chemistry , mangrove , phytochemical , stereochemistry , traditional medicine , terpene , botany , ecology , biochemistry , biology , medicine
The phytochemical examination of the fruits of a Chinese mangrove plant Xylocarpus granatum led to the isolation of five new protolimonoids, protoxylocarpins A–E ( 1 – 5 , resp.), and two new limonoids xylocarpins J and K ( 6 and 7 , resp.), together with xyloccensins M and Y ( 9 and 10 , resp.). Their structures were determined on the basis of extensive spectroscopic data analysis. The cytotoxic activity of the isolated compounds against tumor cell‐lines HCT‐8, Bel‐7402, BGC‐823, and A2780 were evaluated.