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Perchloric Acid–Silica (HClO 4 ⋅SiO 2 )‐Catalyzed Synthesis of 14‐Alkyl‐ or 14‐Aryl‐14 H ‐dibenzo[ a , j ]xanthenes and N ‐[(2‐Hydroxynaphthalen‐1‐yl)methyl]amides
Author(s) -
Das Biswanath,
Kumar D. Nandan,
Laxminarayana Keetha,
Ravikanth B.
Publication year - 2007
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200790134
Subject(s) - chemistry , catalysis , alkyl , perchloric acid , aryl , amide , organic chemistry , medicinal chemistry , urea
The synthesis of 14‐aryl‐ or 14‐alkyl‐14 H ‐dibenzo[ a , j ]xanthenes 3 involving the treatment of naphthalen‐2‐ol ( 1 ) with arenecarboxaldehydes or alkanals 2 in the presence of HClO 4 ⋅SiO 2 as a heterogeneous catalyst was achieved ( Table 1 ), and this reaction was extended to the preparation of N ‐[(2‐hydroxynaphthalen‐1‐yl)methyl]amides 5 by a three‐component reaction with urea ( 4a ) or an amide 4b – d as a third reactant ( Table 2 ).