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Synthesis of Nicotinamide Adenine Dinucleotide (NAD) Analogues with a Sugar Modified Nicotinamide Moiety
Author(s) -
Goulioukitasha,
Wehbe Johny,
Marchand Damien,
Busson Roger,
Lescrinier Eveline,
Heindl Dieter,
Herdewijn Piet
Publication year - 2007
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200790127
Subject(s) - chemistry , nicotinamide adenine dinucleotide , nad+ kinase , nicotinamide , moiety , niacinamide , sugar , stereochemistry , biochemistry , combinatorial chemistry , enzyme
The synthesis of nicotinamide adenine dinucleotide (NAD) analogues in which the ribose unit of the nicotinamide moiety is replaced by a hexitol, altritol, and cyclohexenyl sugar mimic is described.