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New Diterpene Alkaloids from Aconitum sungpanense var. leucanthum
Author(s) -
Yan Hua,
Chen DongLin,
Jian XinXian,
Wang FengPeng
Publication year - 2007
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200790112
Subject(s) - diterpene , aconitum , chemistry , dept , stereochemistry , alkaloid
Five new C 19 diterpene alkaloids, leucanthumsines A ( 1 ), B ( 2 ), C ( 3 ), D ( 4 ), and E ( 5 ), were isolated from the Chinese medicinal herb Aconitum sungpanense var. leucanthum , together with the known C 19 diterpene alkaloids pseudaconine, neoline, 1‐ O ‐methyldelphisine, crassicaudine, chasmanine, talatisamine, indaconitine, ezochansmanine, and leueantine D. The structures of these new alkaloids were elucidated by HR‐MS and advanced NMR methods, including 1 H‐ and 13 C‐NMR (DEPT), 1 H, 1 H‐COSY, HMQC, and HMBC experiments.