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Four New Germine Esters from Veratrum dahuricum
Author(s) -
Tang Jian,
Li HuiLiang,
Shen YunHeng,
Jin HuiZi,
Yan ShiKai,
Liu RunHui,
Zhang WeiDong
Publication year - 2007
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200790078
Subject(s) - chemistry , dept , heteronuclear single quantum coherence spectroscopy , rhizome , stereochemistry , circular dichroism , two dimensional nuclear magnetic resonance spectroscopy , traditional medicine , medicine
Four new alkaloids, compounds 1 – 4 , based on the germine (=4,9‐epoxycevane‐3,4,7,14,15,16,20‐heptol; 5 ) framework, were isolated from the rhizomes of V. dahuricum , together with germine proper. The X‐ray crystal structure of germine ( 5 ) was solved, and all compounds were characterized by circular dichroism, 1D‐ and 2D‐NMR ( 1 H, 1 H‐COSY, DEPT, HSQC, HMBC), as well as HR‐MS analyses.