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C 19 and C 20 Diterpene Alkaloids from Aconitum toxicum Rchb .
Author(s) -
Csupor Dezső,
Forgo Peter,
Csedő Károly,
Hohmann Judit
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690267
Subject(s) - diterpene , aconitum , aconitine , chemistry , alkaloid , stereochemistry , ranunculaceae , terpenoid , botany , chromatography , biology
Abstract Acotoxinine ( 1 ), a new norditerpene alkaloid, was isolated from the roots of Aconitum toxicum Rchb ., together with the structurally related C 19 diterpene alkaloids neoline ( 2 ) and aconitine ( 3 ) and C 20 diterpene alkaloids songorine ( 4 ) and songoramine ( 5 ). The structures were elucidated by HR‐MS and advanced NMR methods, including 1 H‐NMR, JMOD, 1 H, 1 H‐COSY, HSQC, and HMBC experiments. This is the first report of C 20 diterpenoid alkaloids in Aconitum toxicum.