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Molybdate Sulfuric Acid/NaNO 2 : A Novel Heterogeneous System for the N ‐Nitrosation of Secondary Amines under Mild Conditions
Author(s) -
Montazerozohori Morteza,
Karami Bahador
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690261
Subject(s) - chemistry , nitrosation , sulfuric acid , reagent , sodium molybdate , molybdate , molybdenum , sodium nitrite , nano , inorganic chemistry , nuclear chemistry , organic chemistry , chemical engineering , engineering
Wet molybdate sulfuric acid (= dioxo[bis(sulfato‐ κO )]molybdenum; MSA), a new solid acid, can be used in combination with sodium nitrite (NaNO 2 ) to transform a variety of secondary amines to the corresponding N ‐nitroso compounds under mild, heterogeneous conditions ( Table ). The process has several advantages: the reagents are inexpensive and non‐hazardous, the reaction is clean, fast, and high‐yielding, and MSA can be readily removed by filtration and re‐used (after treatment with HCl) without loss of activity. Further, only N ‐nitrosation was observed, but no C ‐ or O ‐nitrosation.