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A Rare New Cleistanthane Diterpene from the Pericarp of Trewia nudiflora
Author(s) -
Du ZhiZhi,
Shen YueMao
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690256
Subject(s) - diterpene , chemistry , terpene , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy
Abstract A minor, unprecedented diterpene, 3 β ,17‐dihydroxycleistantha‐12,15‐dien‐2‐one ( 1 ), was isolated from the CHCl 3 ‐soluble part of the EtOH extract of the pericarp of Trewia nudiflora. The structure of 1 was elucidated by means of 1D‐ and 2D‐NMR spectroscopic analyses as well as by HR‐MS. Also isolated were two known triterpenes, glutin‐5‐en‐3‐ol and olean‐18‐en‐3‐one (germanicone), as well as three known sterols, (22 E ,24 R )‐5 α ,8 α ‐epidioxyergosta‐6,22‐dien‐3 β ‐ol, (22 E ,24 R )‐5 α ,8 α ‐epidioxyergosta‐6,9(11),22‐trien‐3 β ‐ol, and (22 E ,24 R )‐6‐methoxyergosta‐7,22‐dien‐3,5‐diol.