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New Polyoxygenated Triterpenoids from Stachyurus himalaicus var. himalaicus
Author(s) -
Yang JingHua,
Wang YunSong,
Huang Rong,
Luo ShiDe,
Zhang HongBin,
Li Liang
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690254
Subject(s) - chemistry , hela , triterpenoid , stereochemistry , in vitro , terpene , terpenoid , cytotoxic t cell , biochemistry
Abstract Two new polyoxygenated triterpenoids, stachlic acid A (= (2 α ,3 β )‐2,3,23,29‐tetrahydroxyolean‐12‐en‐28‐oic acid; 1 ) and stachlic acid B (= (2 α ,3 α )‐2,29‐dihydroxy‐3,23‐[(1,1‐dimethylmethylene)dioxy]olean‐12‐ene‐28‐oic acid; 2 ), were isolated from Stachyurus himalaicus var. himalaicus. Their structures were established by means of extensive spectroscopic studies and chemical evidence. The purified product 1 was found to have moderate in vitro cytotoxic activity against human Hela cells.