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One‐Pot Synthesis of Pentaalkyl 7‐[(Alkylamino)carbonyl]‐2‐oxa‐1‐azabicyclo[3.2.0]hept‐3‐ene‐3,4,5,6,7‐pentacarboxylate
Author(s) -
Yavari Issa,
Moradi Loghman
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690185
Subject(s) - chemistry , yield (engineering) , alkyl , ene reaction , medicinal chemistry , stereochemistry , organic chemistry , materials science , metallurgy
Dialkyl acetylenedicarboxylates react with alkyl 2‐nitroethanoates in the presence of alkyl isocyanides in a one‐pot reaction to afford the title compounds in 78–90% yield.