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Japonicumins A–D: Four New Compounds from Lycopodium japonicum
Author(s) -
Li XiaoLi,
Zhao Yu,
Cheng Xiao,
Tu Lin,
Peng LiYan,
Xu Gang,
Zhao QinShi
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690148
Subject(s) - chemistry , triterpenoid , terpenoid , lycopodium , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy
Three new serratane‐type triterpenoids, japonicumins A–C ( 1 – 3 ), as well as a unique, new C 13 terpenoid, japonicumin D ( 4 ), were isolated from the dried whole plants of Lycopodium japonicum , together with the known compound lycoclavanol ( 5 ). Their structures were identified by extensive mass‐spectrometric and spectroscopic (especially 2D‐NMR) experiments. Compounds 1 – 5 exhibited no activity against human‐tumor A 549 cells.
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