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Secoiridoid Glycosides from Swertia mileensis
Author(s) -
Zhou Yan,
Di YingTong,
Gesang Suolang,
Peng ShuLin,
Ding LiSheng
Publication year - 2006
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200690016
Subject(s) - chemistry , glycoside , fragmentation (computing) , tandem mass spectrometry , mass spectrometry , stereochemistry , nuclear magnetic resonance spectroscopy , chromatography , computer science , operating system
From the MeOH extract of the aerial parts of Swertia mileensis , four new secoiridoid glycosides were isolated, 4′‐ O ‐[( E )‐caffeoyl]swertiamarin ( 1 ), 4′‐ O ‐[( Z )‐coumaroyl]swertiamarin ( 7 ), 6′‐ O ‐[( E )‐coumaroyl]swertiamarin ( 8 ), and 6′‐ O ‐[( Z )‐coumaroyl]swertiamarin ( 9 ), together with five known compounds. Their structures were elucidated by NMR spectroscopy and tandem mass spectrometry. Detailed HPLC/MS analyses and MS/MS fragmentation pathways are discussed for the identification of the swertiamarin‐derived ( E )/( Z ) isomers 6 / 7 and 8 / 9 .