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New Phenolic Components from Daphne giraldii
Author(s) -
Liao ShangGao,
Zhang BangLe,
Wu Yan,
Yue JianMin
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590230
Subject(s) - chemistry , pinoresinol , hydroxymethyl , stereochemistry , lignan
Two new bis‐coumarins, namely daphnogitin ( 1 ), daphnogirin ( 2 ), and a flavan‐3‐ol derivative, 5‐ O ‐methylafzelechin ( 3 ), together with eleven known compounds, daphnetoxin, 1,2‐dihydrodaphnetoxin, daphnetin, daphnoretin, daphneticin, isodaphneticin, trans ‐2,3‐dihydro‐3‐(4‐hydroxy‐3‐methoxyphenyl)‐2‐(hydroxymethyl)‐9 H ‐pyrano[ 2,3‐f ]‐1,4‐benzodioxin‐9‐one (= demethoxyisodaphneticin; 4b ), (+)‐pinoresinol, acuminatin, (−)‐dihydrosesamin, and isosalicifoline, were isolated from the leaves and stems of Daphne giraldii. Compound 4b was isolated for the first time as a natural product, and 1,2‐dihydrodaphnetoxin, daphneticin, isodaphneticin, (+)‐pinoresinol, acuminatin, (−)‐dihydrosesamin, and isosalicifoline were isolated for the first time from Daphne giraldii. The structures of the three new compounds were elucidated by spectroscopic analysis.