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The Chemical Constituents from the Callus Culture of Trewia nudiflora
Author(s) -
Du ZhiZhi,
Zhao PeiJi,
He HongPing,
Zhu Na,
Hao XiaoJiang,
Shen YueMao
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590178
Subject(s) - chemistry , callus , gallic acid , diterpene , daucosterol , stereochemistry , terpene , triol , glycoside , organic chemistry , botany , column chromatography , diol , biology , antioxidant
Five ent ‐atisane diterpenoids, including three new ones, i.e. , (16 α )‐17‐hydroxy‐ ent ‐atisan‐19‐oic acid methyl ester ( 1 ), (16 α )‐17‐dihydroxy‐ ent ‐atisan‐19‐oic acid methyl ester ( 2 ), (16 α )‐ ent ‐atisan‐16,17,19‐triol ( 3 ), and two known compounds, i.e. , 17‐hydroxy‐ ent ‐atisan‐19‐oic acid ( 4 ), (16 α )‐16,17‐dihydroxy‐ ent ‐atisan‐19‐al ( 5 ), together with one known diterpene glycoside, i.e. , sumogaside, two known triterpenes, i.e. , germanicone and (3 β )‐ β ‐amyrin, three known phenolic compounds, i.e. , (+)‐gallocatechin, (+)‐catechin, and gallic acid, and two known sterols, i.e. , β ‐sitosterol and daucosterol, were isolated from the callus cultures of Trewia nudiflora. Their structures were elucidated by spectroscopic analysis including 1D‐ and 2D‐NMR experiments. No maytansinoids were isolated or detected by LC‐ESI‐MS in the extracts of the calli, which suggests that the callus cultures can not produce maytansinoids under these conditions.