New Briaranes from the South China Sea Gorgonian  Junceella fragilis | Zendy

Qi ShuHua | Zendy; Zhang Si | Zendy; Wen YanMei | Zendy; Xiao ZhiHui | Zendy; Li QingXin | Zendy

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New Briaranes from the South China Sea Gorgonian Junceella fragilis

Author(s) -

Qi ShuHua,

Zhang Si,

Wen YanMei,

Xiao ZhiHui,

Li QingXin

Publication year - 2005

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200590170

Subject(s) - gorgonian , chemistry , coral , stereochemistry , cytotoxicity , carcinoma cell , two dimensional nuclear magnetic resonance spectroscopy , tumor cells , biochemistry , cell , oceanography , in vitro , geology , biology , cancer research

Three new briarane diterpenes, junceellonoids C–E ( 1 – 3 ), along with six known briaranes, junceellin A ( 4 ), praelolide ( 5 ), and junceellolides A‐D ( 6 – 9 ), were isolated from the EtOH/CH 2 Cl 2 extracts of the South China Sea gorgonian coral Junceella fragilis. The structures of 1 – 3 were established by extensive spectroscopic analysis, including 1D‐ and 2D‐NMR data. Compounds 1 and 2 exhibited mild cytotoxicity against human galactophore carcinoma (MDA‐mB‐231 and MCF‐7) cells at the concentration of 100 μ M .

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