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Diterpenoid Alkaloids from Aconitum tanguticum
Author(s) -
Wang YuBo,
Huang Rong,
Zhang HongBin,
Li Liang
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590079
Subject(s) - chemistry , aconitum , terpenoid , alkaloid , stereochemistry , ranunculaceae , two dimensional nuclear magnetic resonance spectroscopy , botany , biology
Abstract A new 19,21‐secohetisan diterpenoid alkaloid, tangutisine B ( 1 ), was isolated from the aerial parts of Aconitum tanguticum ( Maxim. ) Stapf. , together with pacidine, 14‐deacetylajadine. The structure of 1 was determined by an interpretation of 1D‐ and 2D‐NMR together with X‐ray crystallographic data. Bioactivities of the isolates were tested in the P‐388, Bel‐7402, Cox‐2, and caspase‐3 assays.