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Two New Ceramides from the Marine Sponge Ircinia fasciculata
Author(s) -
Zhang GuangWen,
Ma XiangQuan,
Zhang CuiXian,
Su JingYu,
Ye WenCai,
Zhang XiaoQi,
Yao XinSheng,
Zeng LongMei
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590066
Subject(s) - chemistry , ceramide , glycosphingolipid , hydroxymethyl , stereochemistry , sponge , biochemistry , botany , apoptosis , biology
Abstract A new 4‐sulfated ceramide, ircisulfamide (= N ‐[(1 S *,2 S *,3 R *)‐2‐hydroxy‐1‐(hydroxymethyl)‐3‐(sulfooxy)heptadecyl]hexadecanamide; 1 ), and a new glycosphingolipid, ircicerebroside (=(2 R *)‐ N ‐{(1 S *,2 R *,3 E ,7 E )‐1‐[( β ‐ D ‐glucopyranosyloxy)methyl]‐2‐hydroxy‐8‐methylheptadeca‐3,7‐dienyl}‐2‐hydroxyeicosanamide; 2 ), were isolated from the aqueous EtOH extract of the marine sponge Ircinia fasciculata (P allas ). The structures of the new compounds were elucidated on the basis of spectroscopic analysis and by means of chemical methods.