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A Novel Asymmetric ent ‐Kaurane Dimer from Isodon rubescens var. rubescens
Author(s) -
Han QuanBin,
He ZhenDan,
Qiao ChunFeng,
Xu HongXi,
Sun HanDong
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590059
Subject(s) - chemistry , dimer , stereochemistry , moiety , tetrahydrofuran , monomer , organic chemistry , solvent , polymer
A novel asymmetric ent ‐kaurane dimer, xindongnin P ( 1 ), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.