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Three New Triterpenoids from Lycopodium japonicum Thunb
Author(s) -
Yan Jian,
Zhang XiangMing,
Li ZhongRong,
Zhou Lin,
Chen JianChao,
Sun LiRong,
Qiu MingHua
Publication year - 2005
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200590004
Subject(s) - chemistry , triterpenoid , lycopodium , stereochemistry , acetylcholinesterase , organic chemistry , enzyme
Three new triterpenoids, (3 β ,8 β ,14 α ,21 α )‐26,27‐dinoronocerane‐3,8,14,21‐tetrol ( 1 ), (3 β ,8 β ,14 α ,21 β )‐26,27‐dinoronocerane‐3,8,14,21‐tetrol ( 2 ), and lycopodiin A ( 3 ), together with four known compounds, lycoclavanol ( 4 ), lycoclaninol ( 5 ), α ‐onocerin ( 6 ), and 3‐epilycoclavanol ( 7 ), were isolated from Lycopodium japonicum T hunb (Lycopodiaceae). Their structures were established by means of spectroscopic analyses. Compounds 3 and 7 showed moderate antitumor activity. Compounds 4 and 6 exhibited acetylcholinesterase inhibition activity.