cyclo ( β ‐Asp‐ β  3 ‐hVal‐ β  3 ‐hLys) – Solid‐Phase Synthesis and Solution Structure of a Water Soluble  β ‐Tripeptide. Preliminary Communication | Zendy

Büttner Frank | Zendy; Erdélyi Máté | Zendy; Arvidsson Per I. | Zendy

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cyclo ( β ‐Asp‐ β 3 ‐hVal‐ β 3 ‐hLys) – Solid‐Phase Synthesis and Solution Structure of a Water Soluble β ‐Tripeptide. Preliminary Communication

Author(s) -

Büttner Frank,

Erdélyi Máté,

Arvidsson Per I.

Publication year - 2004

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.200490246

Subject(s) - chemistry , tripeptide , side chain , aqueous solution , amide , peptide bond , stereochemistry , peptide , peptide synthesis , combinatorial chemistry , phase (matter) , water soluble , crystallography , organic chemistry , biochemistry , polymer

The H 2 O‐soluble cyclic β 3 ‐tripeptide cyclo( β ‐Asp‐ β 3 ‐hVal‐ β 3 ‐hLys) ( 4 ) was obtained by on‐resin cyclization of the side‐chain‐anchored β ‐peptide 3 ( Scheme ). In aqueous solution, 4 adopts a structure with uniformly oriented amide bonds and all side chains in lateral positions ( Fig. 3 ).

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