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Seven New Norditerpenoid Alkaloids from Spanish Consolida orientalis
Author(s) -
Alva Alenguer,
Grandez Maritza,
Madinaveitia Alberto,
de la Fuente Gabriel,
Gavín José A.
Publication year - 2004
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200490190
Subject(s) - chemistry , ranunculaceae , stereochemistry , alkaloid , terpenoid , botany , biology
Abstract Seven new norditerpenoid alkaloids named 1‐ O ‐demethyltricornine ( 1 ), 14‐ O ‐benzoyltakaosamine ( 2 ), 1‐ O ,19‐didehydrotakaosamine ( 3 ), 14‐ O ‐demethyldelboxine ( 4 ), all belonging to the lycoctonine‐type alkaloids, and 8‐ O ‐methylconsolarine ( 5 ), 14‐ O ‐deacetylpubescenine ( 6 ), and 18‐ O ‐benzoyl‐14‐ O ‐deacetyl‐18‐ O ‐demethylpubescenine ( 7 ), these belonging to the rare group of the 6‐epilycoctonine‐type alkaloids, were isolated from the aerial parts of Consolida orientalis ( Gay ) Schröd . The structures of the new compounds were elucidated by 1D‐ and 2D‐NMR and HR‐EI‐MS. Moreover, 37 known norditerpenoid alkaloids (lycoctonine‐type) were isolated and identified by comparing their spectral data with those reported in the literature.