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Unsymmetrical Unsaturated Ketones from Lactones and Carboxylic Acids in One Step
Author(s) -
Giersch Wolfgang,
Naef Ferdinand
Publication year - 2004
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200490154
Subject(s) - chemistry , scope (computer science) , catalysis , manganese , transformation (genetics) , organic chemistry , carboxylic acid , ketone , lactone , vapor phase , programming language , biochemistry , computer science , gene , physics , thermodynamics
A one‐step transformation of γ ‐ and δ ‐(spiro)lactones into γ , δ ‐ and δ , ε ‐unsaturated ketones in the presence of carboxylic acids in the vapor phase at 400° over a supported manganese catalyst is reported for the first time. The scope of this new transformation is exemplified with a series of lactones, and a mechanistic rationale is proposed.