Steroidal Saponins from Disporopsis pernyi

Four new steroidal saponins, named disporosides A–D ( 1 – 4 ), corresponding to (3 β ,25 R )‐3‐[( β ‐ D ‐glucopyranosyl‐(1→2)‐[ β ‐ D ‐glucopyranosyl‐(1→6)]‐ β ‐ D ‐glucopyranosyl)oxy]‐5 β ‐spirostan ( 1 ), (3 β ,25 R )‐3‐[( β ‐ D ‐glucopyranosyl‐(1→2)‐[6‐ O ‐hexadecanoyl‐ β ‐ D ‐glucopyranosyl‐(1→6)]‐ β ‐ D ‐glucopyranosyl)oxy]‐5 β ‐spirostan ( 2 ), (3 β ,22 R ,25 R )‐26‐[( β ‐ D ‐glucopyranosyl)oxy]‐3‐[( β ‐ D ‐glucopyranosyl‐(1→2)‐ β ‐ D ‐glucopyranosyl)oxy]‐5 β ‐furostan ( 3 ), and (3 β ,22 R ,25 R )‐26‐[( β ‐ D ‐glucopyranosyl)oxy]‐3‐[( β ‐ D ‐glucopyranosyl‐(1→2)‐[ β ‐ D ‐glucopyranosyl‐(1→6)]‐ β ‐ D ‐glucopyranosyl)oxy]‐5 β ‐furostan ( 4 ), have been isolated from the fresh rhizomes of Disporopsis pernyi , together with the three known compounds Ys‐I, agavoside B, and (3 β ,25 R )‐3‐[( β ‐ D ‐xylopyranosyl‐(1→3)‐ β ‐ D ‐glucopyranosyl‐(1→4)‐ β ‐ D ‐galactopyranosyl)oxy]‐5 α ‐spirostan‐12‐one. Their structures were elucidated by spectroscopic analyses, chemical transformations (acid hydrolysis), and comparison with literature data.