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Four Novel Eremophilanolides from Ligularia sagitta
Author(s) -
Li Lyi,
Xu LiWen,
Wang HanQing
Publication year - 2004
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200490103
Subject(s) - chemistry , sagitta , stereochemistry , epoxy , organic chemistry , fishery , fish <actinopterygii> , otolith , biology
Four new eremophilanolides, isolated from Ligularia sagitta , were identified as (1 β ,3 β ,6 β ,8 β ,10 β )‐6‐acetoxy‐3‐(angeloyloxy)‐1,10‐epoxy‐8‐hydroxyeremophil‐7(11)‐en‐8,12 α ‐olide ( 1 ), (1 β ,3 β ,6 β ,8 β ,10 β )‐3‐(angeloyloxy)‐1,10‐epoxy‐6,8‐dihydroxyeremophil‐7(11)‐en‐8,12 α ‐olide ( 2 ), (1 β ,3 β ,6 β ,8 β ,10 β )‐3‐(angeloyloxy)‐1,10‐epoxy‐8‐ethoxy‐6‐hydroxyeremophil‐7(11)‐en‐8,12 α ‐olide ( 3 ), and (1 β ,3 β ,8 β ,10 β )‐3‐(angeloyloxy)‐1,10‐epoxy‐8‐hydroxyeremophil‐7(11)‐en‐8,12 α ‐olide ( 4 ). Their structures were elucidated by spectroscopic methods, including 2D‐NMR techniques and chemical transformations.