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Cyclopeptides and Amides from Pseudostellaria heterophylla (Caryophyllaceae)
Author(s) -
Yang Yabin,
Tan Ninghua,
Zhang Fei,
Lu Yaqing,
He Min,
Zhou Jun
Publication year - 2003
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200390280
Subject(s) - chemistry , caryophyllaceae , stereochemistry , pyroglutamic acid , amino acid , biochemistry , botany , biology
From the roots of Pseudostellaria heterophylla , three cyclopeptides and three amides were isolated, besides heterophyllin A and B. Their structures were determined as cyclo (Ala‐Gly‐Pro‐Val‐Tyr‐) (heterophyllin J; 1 ), cyclo (Ala‐Gly‐Pro‐Tyr‐Leu‐) (pseudostellarin A; 2 ), cyclo (Gly‐Gly‐Gly‐Pro‐Pro‐Phe‐Gly‐Ile‐) (pseudostellarin B; 3 ), methyl γ ‐hydroxypyroglutamate ( 4 ), methyl pyroglutamate ( 5 ), and pyroglutamic acid ( 6 ) on the basis of spectral data, especially 2D‐NMR data. Among them, compounds 1 and 4 are new compounds.