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New Lignan, Benzofuran, and Sesquiterpene Derivatives from the Roots of Leontopodium alpinum and L. leontopodioides
Author(s) -
Dobner Michael J.,
Ellmerer Ernst P.,
Schwaiger Stefan,
Batsugkh Odonchimeg,
Narantuya Samdan,
Stütz Michaela,
Stuppner Hermann
Publication year - 2003
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200390072
Subject(s) - chemistry , lignan , benzofuran , sesquiterpene , derivative (finance) , stereochemistry , coumarin , tetrahydrofuran , coniferyl alcohol , organic chemistry , lignin , solvent , financial economics , economics
Three new compounds, including a benzofuran, 1‐{(2 R *,3 S *)‐3‐( β ‐ D ‐glucopyranosyloxy)‐2,3‐dihydro‐2‐[1‐(hydroxymethyl)vinyl]‐1‐benzofuran‐5‐yl}ethanone ( 1 ), a lignan, [(2 S ,3 R ,4 R )‐4‐(3,4‐dimethoxybenzyl)‐2‐(3,4‐dimethoxyphenyl)tetrahydrofuran‐3‐yl]methyl (2 E )‐2‐methylbut‐2‐enoate ( 2 ), and a silphiperfolene‐type sesquiterpene, [(1 S ,2 Z ,3a S ,5a S ,6 R ,8a R )‐1,3a,4,5,5a,6,7,8‐octahydro‐1,3a,6‐trimethylcyclopenta[ c ]pentalen‐2‐yl]methyl acetate ( 3 ), together with the known coumarins obliquin ( 4 ) and its 5‐methoxy derivative 5 were isolated from the roots of Leontopodium alpinum. Another known coumarin derivative, 5‐hydroxyobliquin ( 6 ), was isolated from the roots of L. leontopodioides. The structures of these compounds were established by spectroscopic studies.