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On the Reactivity of 1 H ‐Pyrazino[2,3‐ c ][1,2,6]thiadiazine 2,2‐Dioxide and Derivatives: Nucleophilic Substitution, Amination, Aldol‐Type Condensation, Oxidation, and Hydrolysis
Author(s) -
Campillo Nuria,
Páez Juan Antonio,
Goya Pilar
Publication year - 2003
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.200390003
Subject(s) - chemistry , reactivity (psychology) , amination , pteridine , aldol condensation , hydrolysis , nucleophilic substitution , medicinal chemistry , condensation , organic chemistry , stereochemistry , catalysis , medicine , physics , alternative medicine , pathology , thermodynamics , enzyme
The reactivity of the 1 H ‐pyrazino[2,3‐ c ][1,2,6]thiadiazine 2,2‐dioxide system, structurally related to pteridine, was studied, and a number of novel derivatives were synthesized. The chemical behaviors of these two related fused polyaza systems were compared.