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A Synthetic Receptor for β,β‐Carotene: Towards an enzyme mimic for central cleavage
Author(s) -
French Richard R.,
Wirz Jakob,
Woggon WolfDietrich
Publication year - 1998
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19980810555
Subject(s) - chemistry , dimer , binding constant , cleavage (geology) , cyclodextrin , fluorescence , porphyrin , stereochemistry , phenol , condensation , binding site , enzyme , photochemistry , organic chemistry , biochemistry , physics , geotechnical engineering , quantum mechanics , fracture (geology) , engineering , thermodynamics
We report on the synthesis of a receptor 4 for β,β‐carotene ( 1 ), and on the binding interaction between the two which yields inclusion complex 5 . The cyclodextrin ‘dimer’ 4 was obtained via condensation of the corresponding 4,4′‐(porphyrin‐5,15‐diyl)bis phenol 8 with 6 A ‐deoxy‐6 A ‐iodo‐β‐cyclodextrin ( 6 ) in the presence of Cs 2 CO 3 . Fluorescence studies of the binding interaction between ‘dimer’ 4 and β,β‐carotene ( 1 ) gave a binding constant K a of (2.4 ± 0.1) · 10 6 M −1 .
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