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Photolysis of Steroidal 20‐Aryl‐Substituted 11‐Nitrites
Author(s) -
Kalvoda Jaroslav,
Grob Jüren,
Bjelakovíć Mira,
Lorenc Ljubinka,
Mihailovíć Mihailo Lj.
Publication year - 1997
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19970800419
Subject(s) - chemistry , nitrous acid , photodissociation , aryl , derivative (finance) , nitro , medicinal chemistry , stereochemistry , organic chemistry , alkyl , financial economics , economics
The two structurally similar 20‐phenyl‐ and 20‐(4‐methoxyphenyl)‐11‐(nitrosooxy)pregnan‐20‐ol derivatives 4 and 7 behave differently under photolytic conditions, the former nitrous acid ester affording, as a main product, the benzo‐fused hexacyclic compound 9 , and the latter the 21 ‐nitro derivative 12. Mechanistic aspects of these transformations are discussed.