Ein alternativer Zugang zum PQQ‐Triester | Zendy

Sicker Dieter | Zendy; Stehfest Ekkehard | Zendy; Wilde Horst | Zendy; Martin Pierre | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Ein alternativer Zugang zum PQQ‐Triester

Author(s) -

Sicker Dieter,

Stehfest Ekkehard,

Wilde Horst,

Martin Pierre

Publication year - 1996

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19960790309

Subject(s) - chemistry , annulation , quinoline , block (permutation group theory) , redox , stereochemistry , catalysis , organic chemistry , geometry , mathematics

An Alternative Approach to the PQQ‐Triester A novel approach to triethyl 5‐methoxy‐1 H ‐pyrrolo[2,3‐ f ]quinoline‐2,7,9‐tricarboxylate ( 6 ), a close precursor of the redox cofactor PQQ of bacterial dehydrogenases, is described. Diethyl 2‐oxopent‐3‐ynedioate ( 5 ) was used as building block for the annelation of the quinoline unit. The annelation proceeds in two steps via the diastereoselective formation of diethyl ( Z )‐4‐{[2‐(ethoxycarbonyl)‐5‐methoxyindol‐6‐yl]amiono}‐2‐oxopent‐3‐enedioate (( Z )‐ 7 ) followed by acid‐catalyzed cyclocondensation.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research