Premium
New Triterpene Saponins from Herniaria glabra
Author(s) -
Freiler Michaela,
Reznicek Gottfried,
Jurenitsch Johann,
Kubelka Wolfgang,
Schmidt Wolfram,
SchubertZsilavecz Manfred,
Haslinger Ernst,
Reiner Josef
Publication year - 1996
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19960790207
Subject(s) - chemistry , saponin , triterpene , stereochemistry , two dimensional nuclear magnetic resonance spectroscopy , traditional medicine , medicine , alternative medicine , pathology
Three new saponins 1–3 were isolated from Herniaria glabra by means of prep. HPLC and TLC. The structures were established mainly by a combination of 2D‐NMR techniques (COSY, TOCSY, ROESY, HMQC, and HMBC) as O ‐α‐ L ‐rhamnopyranosyl‐(1→4)‐ O ‐β‐ D ‐glucopyranosyl‐(1‐→6)‐ O ‐[β‐ D ‐glucopyranosyl‐(1→2)]‐β‐ D ‐glucopyranosyl medicagen‐28‐ate (herniaria saponin 4; 1 ), O ‐β‐ D ‐glucopyranosyl‐(1→3)‐ O ‐α‐ L ‐rhamnopyranosyl‐(1→2)‐ O ‐[β‐(3 R )‐ D ‐apiofuranosyl‐(1→3)]‐β‐ D ‐4‐ O ‐acetylfucopyranosyl 3‐ O ‐(β‐ D ‐glucuronopyranosyl)‐16α‐hydroxymedicagen‐28‐ate (herniaria saponin 5; 2 ), and O ‐α‐ L ‐rhamnopyranosyl‐(1→4)‐ O ‐β‐ D ‐glucopyranosyl‐(1→6)‐ O ‐[β‐ D ‐6‐ O ‐acetylglucopyra nosyl‐(1→2)]‐β‐ D ‐glucopyranosyl medicagen‐28‐ate (herniaria saponin 6; 3 ).